News & Discoveries

May 06, 2020

Self-Corrective Mechanism at Synapse Doubles Lifespan for Mice with ALS, Suggests New Approach to Therapy for Human Brain Diseases UCSF researchers have identified a powerful self-corrective mechanism within synapses that is activated by neurodegeneration and acts to slow down disease progression in animal models of ALS.

April 28, 2020

Researchers Honored for Fundamental Insights into Brain Development and Molecular ImagingThe two from UCSF are among 120 new members elected to the Academy in 2020.

March 10, 2020

UC San Francisco researchers have finally identified the cellular circuit responsible for conveying stress signals from inside mitochondria to the integrated stress response, a discovery that may have important implications for treating the many debilitating diseases associated with mitochondrial stress.

March 09, 2020

A new UCSF study of patients with Parkinson’s disease has revealed a pathway that transmits signals very rapidly between two parts of the human brain to govern the complex act of halting a motion once it’s been initiated.

March 05, 2020

UCSF scientists have made a significant advance toward understanding a rare genetic condition, almost exclusively affecting females, that results in a broad spectrum of neurodevelopmental deficits.

March 02, 2020

A simple blood test may soon be able to diagnose patients with two common forms of dementia – Alzheimer’s disease and frontotemporal dementia – and tell the two apart.

March 02, 2020

Plasma Marker May Flag Alzheimer’s as Cause of Mild Cognitive Impairment, UCSF-Led Study ShowsA blood test that may eventually be done in a doctor’s office can swiftly reveal if a patient with memory issues has Alzheimer’s disease or mild cognitive impairment and can also distinguish both conditions from frontotemporal dementia.

February 10, 2020

Study in Mice Adds to Evidence for Overlooked Role of Myelin in Long-Term Memory StorageFor a conditioned response to become long-lasting requires brain cells to increase amounts of an insulating material called myelin, which may serve to reinforce and stabilize newly formed neural connections.

February 06, 2020

Removing Surrounding Tissue Adds Ammunition to Battle Against Lethal Disease, UCSF-Led Study ShowsSurvival may more than double for adults with glioblastoma, if neurosurgeons remove the surrounding tissue as aggressively as they remove the cancerous core of the tumor.

February 03, 2020

UCSF researchers are working on deep-brain stimulation technology that can be customized to the patient’s brain make up and their own brain’s feedback.