News & Discoveries

Scientists Find a Mechanism for How Exercise Protects the Brain

A UCSF team finds a liver protein, released with exercise, that improves memory in aging and Alzheimer’s disease by repairing the brain’s blood vessels. It's the missing link between exercise and brain rejuvenation that many have been hunting for.

The Brain May Learn More from Rare Events than from Repetition

UCSF research upends 100-year-old assumption about Pavlov’s dog and associative learning. How we learn to predict an outcome isn’t determined by how many times a cue and reward happen together. Instead, how much time passes between rewards is also important. Understanding this process has…

Decoding Parkinson’s Patients’ Movements in the Real World

In a first-of-its-kind study, UCSF researchers use brain signals recorded at home to identify when patients are walking. For years, scientists have studied how the brain controls movement by asking patients to perform structured tasks while connected to multiple sensors in a lab. While these…

Immune Cells Linked to Epstein-Barr Virus May Play a Role in MS

A study from UCSF shows a previously unknown connection between the Epstein-Barr virus, known to play a role in MS, and an understudied type of immune cell.

Rewriting the Story of Estrogen

The hormone’s role in women’s health reaches far beyond reproduction. The hormone’s role in women’s health reaches far beyond reproduction.

This Cellular Hazmat Team Cleans Up Tau. Can It Prevent Dementia?

Researchers found a "garbage man" enzyme that tags toxic clumps of proteins in the brain for removal, and saw a correlation with resilience against dementia.

Improving Future Alzheimer’s Treatment by Guiding Today’s Breakthroughs

UCSF’s Renaud La Joie leads Alzheimer’s Association consortium developing treatment framework for Alzheimer’s patients in the era of anti-amyloid therapies. In the last few years, progress has been made in the fight against Alzheimer’s disease with a class of therapies called anti-amyloid…

Your Pain Meds’ Side Effects May Be Masquerading as Heart Failure

Matthew Growdon's study finds "prescription cascades" where drug side effects lead to unnecessary second prescriptions, causing further harm and costly hospitalizations.

Why a Foreign Language Sounds Like a Blur to Non-Native Ears

Two new UCSF studies reveal how the brain learns to divide sentences into words. Scientists have thought that when we hear language, the brain processes it the same way, whether it's familiar or foreign. A new study reveals that exposure to a language changes how certain clusters of neurons…

Some Children’s Tantrums Can Be Seen in the Brain, New Study Finds

Scanning the brains of children with sensory processing disorder, scientists see in some a struggle to gain self-control and minimize outside stimulation. New research shows how brain networks differ in neurodiverse children who are and aren't resilient in the face of sensory overload.